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1994-09-03
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Document 0120
DOCN M9490120
TI Acquired immunodeficiency syndrome in the elderly.
DT 9411
AU Adler WH; Nagel JE; Clinical Immunology Section, National Institute on
Aging,; National Institutes of Health, Baltimore, Maryland.
SO Drugs Aging. 1994 May;4(5):410-6. Unique Identifier : AIDSLINE
MED/94319076
AB Recent data from the US show that since 1990 the number of paediatric
patients with AIDS is decreasing while the number of patients with AIDS
over age 50 years is increasing. To date, little attention has been
given to understanding AIDS risk-taking behaviours, clinical
presentations, and therapeutic needs of middle-aged and older
HIV-infected individuals. Older HIV-infected individuals deteriorate
more rapidly than younger patients due to an accelerated loss of CD4+
helper T cells. Despite recognised age-related physiological differences
between young and elderly individuals, scant information about drug
optimisation for the treatment of AIDS in older individuals is
available. More data need to be collected about this group of AIDS
patients, and appropriate treatment strategies designed for their
special needs.
DE Acquired Immunodeficiency Syndrome/DRUG THERAPY/*EPIDEMIOLOGY/
ETIOLOGY/*IMMUNOLOGY Aged Aging/*IMMUNOLOGY/PHYSIOLOGY Blood
Transfusion/ADVERSE EFFECTS Human Immunity, Cellular Prognosis
Social Isolation Zidovudine/ADVERSE EFFECTS JOURNAL ARTICLE REVIEW
REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).